Characterizing the Regulation of tfoX in Vibrio fischeri
نویسنده
چکیده
Natural transformation describes how some bacteria can incorporate exogenous DNA into their genome and acquire new traits. This phenomenon occurs in Vibrios and is induced by the biopolymer chitin. In Vibrios, TfoX is a primary regulator of natural transformation. The mechanisms underlying chitin-induced natural transformation and activation of TfoX in Vibrio fischeri remain unclear. This project examines the response of tfoX expression to various genetic factors and environmental signals, such as N-acetyl-glucosamine, which is derived from chitin. The findings from this study will help us construct a model for the regulatory pathway of tfoX in Vibrio fischeri.
منابع مشابه
Natural transformation of Vibrio fischeri requires tfoX and tfoY.
Recent evidence has indicated that natural genetic transformation occurs in Vibrio cholerae, and that it requires both induction by chitin oligosaccharides, like chitohexaose, and expression of a putative regulatory gene designated tfoX. Using sequence and phylogenetic analyses we have found two tfoX paralogues in all sequenced genomes of the genus Vibrio. Like V. cholerae, when grown in chitoh...
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